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64.25 mg sitagliptin monohydrate equivalent to 50 mg of sitagliptin and 389.93 mg of metformin equivalent to 500 mg metformin HCl (JANUMET 50/500). 64.25 mg sitagliptin monohydrate equivalent to 50 mg of sitagliptin and 779.86 mg of metformin equivalent to 1000 mg metformin HCl (JANUMET 50/1000).

For oral dosage form (immediate-release tablets): For patients taking metformin alone: Adults—At first, 50 milligrams (mg) of sitagliptin, plus the dose of metformin already being taken, 2 times per day. Your doctor may gradually increase your dose until your blood sugar is controlled. If you are taking 850 mg of metformin 2 times per day.

JANUMET is a combination of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin hydrochloride (HCl), a biguanide, indicated as an adjunct to diet and exercise to improve.

Sitagliptin, which is approved for treatment of type 2 diabetes mellitus, is an inhibitor of T cell costimulation that may be effective against aGVHD in combination with Tac and Sir. Sitagliptin is … Treatment of type 2 diabetes mellitus in the older patient Kidney transplantation in adults: Posttransplantation diabetes mellitus