Signs and symptoms of anemia

  1. Anemia: Signs and Symptoms
  2. Thalassemia: Causes, Symptoms, Diagnosis, and Treatment


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Anemia: Signs and Symptoms

Sherri Gordon, CLC is a certified professional life coach, author, and journalist covering health and wellness, social issues, parenting, and mental health. She also has a certificate of completion from Ohio State's Patient and Community Peer Review Academy where she frequently serves as a community reviewer for grant requests for health research. • National Heart, Lung, and Blood Institute. • Rhodes CE, Denault D, Varacallo M. StatPearls. StatPearls Publishing; 2023. • Hanif N, Anwer F. StatPearls. StatPearls Publishing; 2023. • MedlinePlus. • Auerbach M, Adamson JW. Am J Hematol. 2016;91(1):31-8. doi:10.1002/ajh.24201 • Turner J, Parsi M, Badireddy M. StatPearls. StatPearls Publishing; 2023. • Tayyebi A, Poursadeghfard M, Nazeri M, Pousadeghfard T. Int J Hematol Oncol Stem Cell Res. 2019;13(3),164–171. • Gür-Özmen S, Karahan-Özcan R. Pain Med. 2015:pnv029. doi:10.1093/pm/pnv029 • Ma Z, Jiang H, Meng C, Cui S, Peng J, Wang J. PLoS One. 2020;15(7):e0236828. doi:10.1371/journal.pone.0236828 • Stugiewicz M, Tkaczyszyn M, Kasztura M, Banasiak W, Ponikowski P, Jankowska EA. Eur J Heart Fail. 2016;18(7):762-773. doi:10.1002/ejhf.467 • MedlinePlus. • Lee WH, Hsu PC, Chu CY, et al. Int J Med Sci. 2015;12(8):618-624. doi:10.7150/ijms.11924 • Moiz B. Clin Case Rep. 2018;6(3):547-548. doi:10.1002/ccr3.1404 • Salinas M, Leiva-Salinas M, Flores E, López-Garrigós M, Leiva-Salinas C. Adv Hematol. 2020;2020:7341018. doi:10.1155/2020/7341018 • Goluch-Koniuszy ZS. Prz Menopauzalny. 2016;15...

Thalassemia: Causes, Symptoms, Diagnosis, and Treatment

What is thalassemia? Thalassemia is an inherited blood disorder in which the body makes an abnormal form of hemoglobin. Hemoglobin is the protein molecule in red blood cells that carries oxygen. The disorder results in excessive destruction of red blood cells, which leads to Thalassemia is inherited, meaning that at least one of your parents must be a carrier of the disorder. It’s caused by either a genetic mutation or a deletion of certain key gene fragments. Thalassemia minor is a less serious form of the disorder. There are two main forms of thalassemia that are more serious. In alpha thalassemia, at least one of the alpha globin genes has a mutation or abnormality. In beta thalassemia, the beta globin genes are affected. Each of these forms of thalassemia has different subtypes. The exact form you have will affect the severity of your symptoms and your outlook. Thalassemia occurs when there’s an abnormality or mutation in one of the genes involved in hemoglobin production. You inherit this genetic abnormality from your parents. If only one of your parents is a carrier for thalassemia, you may develop a form of the disease known as thalassemia minor. If this occurs, you probably won’t have symptoms, but you’ll be a carrier. Some people with thalassemia minor do develop minor symptoms. If both of your parents are carriers of thalassemia, you have a greater chance of inheriting a more serious form of the disease. There are three main types of thalassemia (and four subtype...