Sodium nitroprusside formula

Sodium Nitroprusside Injection is not suitable for direct injection. The solution must be further diluted in sterile 5% dextrose injection before infusion. Sodium Nitroprusside can cause precipitous decreases in blood pressure (see ). In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death. Sodium nitroprusside should be used only when available equipment and personnel allow blood pressure to be continuously monitored. Except when used briefly or at low (< 2 mcg /kg /min) infusion rates, sodium nitroprusside gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see ). The usual dose rate is 0.5-10 mcg /kg /min, but infusion at the maximum dose rate should never last more than 10 minutes. If blood pressure has not been adequately controlled after 10 minutes of infusion at the maximum rate, administration of sodium nitroprusside should be terminated immediately. Although acid-base balance and venous oxygen concentration should be monitored and may indicate cyanide toxicity, these laboratory tests provide imperfect guidance. DESCRIPTION Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, a hypotensive agent whose structural formula is Sodium Nitroprusside whose molecular formula is Na2[Fe(CN)5NO] • 2H 2 O, and whose molecular weight is 297.95. Dry sodium nitroprusside is a reddish-brown powder, soluble in water. In an aqueous solution infused intravenously, sod...

What Is Nipride RTU? Nipride RTU (sodium nitroprusside) in 0.9% sodium chloride injection is a direct acting vasodilator indicated for immediate reduction of blood pressure; producing controlled What Are Side Effects of Nipride RTU? Common side effects of Nipride RTU can be serious and include: • • • thiocyanate toxicity, • blood disorder ( • increases in intracranial pressure. Less common side effects of Nipride RTU include: • slow or fast heart rate, • rash, • nausea, • abdominal pain, • muscle • dizziness, • headache, • flushing, • sweating, • red streaking along the veins, and • irritation at the infusion site. Dosage for Nipride RTU Initiate infusion of Nipride RTU at a rate of 0.3 mcg/kg/min, and titrate every few minutes until the desired effect is achieved OR the maximum recommended infusion rate of 10 mcg/kg/min has been reached. Seek medical care or call 911 at once if you have the following serious side effects: • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out; • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors. This document does not contain all possible side effects and o...

Sodium Nitroprusside Injection is not suitable for direct injection. The solution must be further diluted in sterile 5% dextrose injection before infusion. Sodium Nitroprusside Injection can cause precipitous decreases in blood pressure (see ). In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death. Sodium nitroprusside should be used only when available equipment and personnel allow blood pressure to be continuously monitored. Except when used briefly or at low (< 2 mcg/kg/min) infusion rates, sodium nitroprusside gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see ). The usual dose rate is 0.5 to 10 mcg/kg/min, but infusion at the maximum dose rate should never last more than 10 minutes. If blood pressure has not been adequately controlled after 10 minutes of infusion at the maximum rate, administration of sodium nitroprusside should be terminated immediately. Although acid-base balance and venous oxygen concentration should be monitored and may indicate cyanide toxicity, these laboratory tests provide imperfect guidance. DESCRIPTION Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, a hypotensive agent whose structural formula is Sodium Nitroprusside whose molecular formula is Na2[Fe(CN)5NO] • 2H2O, and whose molecular weight is 297.95. Dry sodium nitroprusside is a reddish-brown crystals or powder, freely soluble in water. In an aqueous solution ...

WARNING: (A) EXCESSIVE HYPOTENSION; (B) CYANIDE TOXICITY (A) EXCESSIVE HYPOTENSION: Sodium Nitroprusside can cause precipitous decreases in blood pressure which can lead to irreversible ischemic injuries or death. Use only with continuous blood pressure monitoring [see Dosage and Administration ( (B) CYANIDE TOXICITY: Sodium nitroprusside metabolism produces dose-related cyanide, which can be lethal. A patient’s ability to buffer cyanide will be exceeded in less than one hour at the maximum dose rate (10 mcg/kg/min); limit infusions at the maximum rate to as short a duration as possible [see Warnings and Precautions ( Indications and Usage for Nipride RTU Immediate Reduction of Blood Pressure Sodium nitroprusside is indicated for the immediate reduction of blood pressure of adult and pediatric patients in hypertensive crises. Induction and Maintenance of Controlled Hypotension Sodium nitroprusside indicated for induction and maintenance of controlled hypotension in adults and children during surgery, to reduce bleeding. Treatment of Acute Heart Failure Sodium nitroprusside is indicated for the treatment of acute heart failure to reduce, left ventricular end-diastolic pressure, pulmonary capillary wedge pressure, peripheral vascular resistance and mean arterial blood pressure. Related/similar drugs Nipride RTU Dosage and Administration Inspection Inspect parenteral drug products for particulate matter and discoloration prior to administration, whenever solution and containe...

The correct option is D sodium pentacyanonitrosylferrate(II) The formula of sodium nitroprusside is N a 2 [ F e ( C N ) 5 N O ]. The name of sodium cation is written first, the names of ligands are written in alphabetical order. hence ''cyano'' will be written prior to "nitrosyl''. The name of iron metal is written as ferrate. Oxidation state of Fe be "x" x + 5 × ( − 1 ) + 1 × ( + 1 ) = − 2 x = + 2 Therefore, name of the complex is sodium pentacyanonitrosylferrate(II). The roman numeral (II) indicates oxidation state.

BOXED WARNING Sodium Nitroprusside Injection is not suitable for direct injection. The solution must be further diluted in sterile 5% dextrose injection before infusion. Sodium nitroprusside can cause precipitous decreases in blood pressure (see DOSAGE AND ADMINISTRATION). In patients not properly monitored, these decreases can lead to irreversible ischemic injuries or death. Sodium nitroprusside should be used only when available equipment and personnel allow blood pressure to be continuously monitored. Except when used briefly or at low (<2 mcg/kg/min) infusion rates, sodium nitroprusside gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see WARNINGS). The usual dose rate is 0.5 to10 mcg/kg/min, but infusion at the maximum dose rate should never last more than 10 minutes. If blood pressure has not been adequately controlled after 10 minutes of infusion at the maximum rate, administration of sodium nitroprusside should be terminated immediately. Although acid-base balance and venous oxygen concentration should be monitored and may indicate cyanide toxicity, these laboratory tests provide imperfect guidance. DESCRIPTION Sodium nitroprusside is disodium pentacyanonitrosylferrate(2-) dihydrate, a hypotensive agent whose structural formula is Sodium Nitroprusside whose molecular formula is Na 2 [Fe(CN) 5 NO] • 2H 2 O, and whose molecular weight is 297.95. Dry sodium nitroprusside is a reddish-brown powder, soluble in water. I...

What Is Nitroprusside Test? Nitroprusside test is a biochemical test used for the detection of the free-SH groups in amino acids or the cysteine amino acid in a protein. This test uses sodium Nitroprusside reagents and ammonia solution. Nitroprusside is a complex anion consisting of an octahedral ferrous center which is surrounded by five tightly bound cyanide groups. In this test, the thiol groups (cysteine) react with sodium Nitroprusside in the presence of excess ammonia to give a red or purple color. Nitroprusside test is commonly used to detect the presence of ketones in the urine. The test can also be used for the differentiation between cysteine and cystine as cysteine gives a positive result to this test but cystine does not. Objective of Nitroprusside Test • To detect the presence of cysteine in the urine sample and diagnose cystinuria. • To detect the presence of amino acid cysteine in a protein solution. • To differentiate between the amino acids cysteine and cystine. Principle of Nitroprusside Test The test is based on the detection of free sulfur atoms in a solution as a result of the degradation of the –SH group. In other words, the Nitroprusside test is specific for cysteine, the only amino acid containing sulfhydryl group (-SH). The testing principle is that the free-SH group called thiol or mercapto, which is contained in the amino acid cysteine will react with Nitroprusside in the case of excess ammonia to form red compounds. The S-S-group in cysteine wil...