Cefpodoxime proxetil dispersible tablets uses

Identification Summary Cefpodoxime is a third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis. Generic Name Cefpodoxime DrugBank Accession Number DB01416 Background Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. Type Small Molecule Groups Approved, Vet approved Structure Learn more Pharmacodynamics Cefpodoxime is shown to be effective against most Gram positive and Gram negative bacteria, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. Mechanism of action Cefpodoxime is active against a wide spectrum of Gram-positive and Gram-negative bacteria. Cefpodoxime is stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and cephalosporins, due to their production of beta-lactamase, may be susceptible to cefpodoxime. Cefpodoxime is inactivated by certain extended spectrum beta-lactamases. The bactericidal activity of cefpodoxime results from its inhibition of cell wall synthesis. The active metabolite of cefpodoxime binds preferentially to penicillin binding protein 3, which inhibits production of peptidoglycan, the primary constituent ...

You or your child must take the tablets with food, while the oral liquid may be taken with or without food. Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. • For oral dosage forms (suspension or tablets): • For bronchitis: • Adults and teenagers 12 years of age and older—200 milligrams (mg) every 12 hours. • Children younger than 12 years of age—Use and dose must be determined by your doctor. • For ear infections: • Infants and children 2 months to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg)...

What Are Dosages of Cefpodoxime? Dosages of Cefpodoxime: Adult and Pediatric Dosages: Oral suspension • 50 mg/5 ml • 100 mg/5 ml Tablet • 100 mg • 200 mg Dosage Considerations – Should be Given as Follows: • 200 mg orally every 12 hours for 10 days Acute Community- • 200 mg orally every 12 hours for 14 days Acute Maxillary Adult • 200 mg orally every 12 hours for 10 days Pediatric • Infants under 2 months: safety and efficacy not established • Infants 2 months – Children 12 years: 5 mg/kg orally every 12 hours for 10 days; individual doses not to exceed 200 mg • Children over 12 years: 200 mg orally every 12 hours for 10 days Adult • 100 mg orally every 12 hours for 5-10 days Pediatric • Infants under 2 months: safety and efficacy not established • Infants 2 months – Children 12 years: 5 mg/kg orally every 12 hours for 5-10 days; individual doses not to exceed 100 mg • Children over 12 years: 100 mg orally every 12 hours for 5-10 days Skin/Skin Structure Infections • 400 mg orally every 12 hours for 7-14 days • Uncomplicated gonorrhea in men and women; • 200 mg orally once Uncomplicated • 100 mg orally every 12 hours for 7-14 days Pediatric • Infants under 2 months: safety and efficacy not established • Infants 2 months – Children 12 years: 5 mg/kg orally every 12 hours for 5 days; individual doses not to exceed 200 mg • Children over 12 years: 200 mg orally every 12 hours for 5 days Dosing Modifications Renal impairment • Creatinine clearance under 30 ml/min: give every 2...

Description and Brand Names Drug information provided by: US Brand Name • Vantin Descriptions Cefpodoxime is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.