Pantoprazole tablets ip

Introduction Pantoprazole, a substituted pyridyl methylsulfinyl benzimidazole, is a proton-pump inhibitor (PPI) that is similar in structure and mechanism of action to other acid-activated antiulcer drugs, such as omeprazole, lansoprazole, and rabeprazole. PPIs are weak bases, with a pKa of about 4. Their stability in aqueous solution is pH dependent; the rate of degradation increases with decreasing pH. [ [ Table 1. Stability of Pantoprazole Oral Liquid at 2-8 °C [ Initial Concentration (mg/mL) % Initial Concentration Remaining 8 Days 15 Days 22 Days 34 Days 49 Days 62 Days 2.02 ± 0.02 95.1 ± 1.3 95.8 ± 1.0 96.1 ± 1.1 96.4 ± 1.6 95.7 ± 1.1 96.4 ± 0.9 a Values are mean ± S.D. for six samples measured in duplicate (n = 6). Authors and Disclosures Paul J. Dentinger, M.S., is Chemist and Chad F. Swenson, B.S., is Supervisor of Manufacturing, Department of Pharmacy, Strong Memorial Hospital, Rochester, NY. Nasr H. Anaizi, PH.D., is Clinical Pharmacist, Department of Pharmacy, and Associate Professor, Department of Pharmacology and Physiology, University of Rochester, Rochester. Sidebar: Appendix: Procedure for compounding pantoprazole oral liquid • Remove the Protonix imprint from each of 20 pantoprazole 40-mg tablets by gently rubbing the tablets on a paper towel that has been dampened with ethanol.a • Allow the tablets to air dry for a few minutes. • Triturate the tablets to a coarse powder by using a mortar and pestle. • Transfer the powder to a 600-mL beaker and add 340 mL...

Read the Take this medication by If you are taking the tablets, you may take them with or without food. Swallow the tablets whole. Do not split, crush, or chew the medication. Doing so may destroy the drug. If you are taking the granules, take your dose 30 minutes before a meal. To take it by If you are giving the granules through a tube into the If needed, antacids may be taken along with this medication. If you are also taking sucralfate, take pantoprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better. Tell your doctor if your condition lasts or gets worse. The risk of side effects goes up over time. Ask your doctor how long you should take this medication. Remember that this Tell your doctor right away if you have any serious side effects, including: symptoms of a low This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: If you have these symptoms, do not use anti- Rarely, proton pump inhibitors (such as A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor...

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If you have problems with your It’s a prescription drug that’s used to: • treat erosive • help heal damage to the esophagus that’s caused by erosive esophagitis with GERD in adults • treat conditions, such as Depending on the condition being treated, pantoprazole oral tablets can be used in adults and some children. To learn more about these conditions and how pantoprazole is used for them, see the “ Pantoprazole oral tablet basics Pantoprazole belongs to a group of drugs called You’ll take pantoprazole oral tablets by mouth. Note: Pantoprazole also comes as an injection and an oral suspension (a type of liquid mixture). Only the oral tablet is described in this article. If you’d like to learn about pantoprazole’s other forms, talk with your doctor or pharmacist. Pantoprazole oral tablet brand-name versions Pantoprazole oral tablets are a Pantoprazole oral tablets are a generic drug, which means they’re an exact copy of the active drug in a brand-name medication. The brand-name medication that pantoprazole is based on is called Protonix. Generic drugs are thought to be as safe and effective as the brand-name drug they’re based on. In general, generics usually cost less than brand-name drugs. If you’d like to know more about using Protonix instead of pantoprazole, talk with your doctor. Read this Like most drugs, pantoprazole oral tablets may cause mild or serious side effects. The lists below describe some of the more common side effects that pantoprazole may cause. These ...

Amzor Healthcare is dedicated to the ailing mankind and cares for the life, thus, stands out to be the top Pharmaceutical Company in India. We are known for delivering what we commit to our stakeholders, business partners, customers, patients, employees, investors and everyone who so ever is connected with the company. Description Pantoprazole Tablets IP 40 Mg contains an active substance Pantoprazole. This medicine is used in adolescents (12 years or above) and adults. It treats Reflux oesophagitis (an inflammation of the esophagus accompanied by stomach acid regurgitation). In addition, this medicine is effective in Zollinger-Ellison-Syndrome. Also, It is used in patients with duodenal ulcers and stomach ulcers in combination with other antibiotics. Mechanism of Action:- Pantoprazole is an active substance in this medicine. It belongs to the drug category of proton pump inhibitor (PPI). It functions by inhibiting the final the of gastric acid production by creating a covalent bond. This medicine targets two sites of (H+, K+)-ATPase enzyme system of the gastric parietal cell at secretary surface. To simplify, this medicine reduces the acid production in the stomach, which alleviates the symptoms, such as indigestion, heartburn, etc. Know Before Using Pantoprazole Tablets IP 40 mg An individual patient should not take this medicine if allergic to Pantoprazole tablets or any of its ingredients. An individual can get a list of ingredients from the pharmacist. Also, do not ta...

Pantoprazole is indicated for use in adults and adolescents 12 years of age and above for: - Reflux oesophagitis. Pantoprazole is indicated in adults for: - Eradication of Helicobacter pylori ( H. pylori) in combination with appropriate antibiotic therapy in patients with H. pylori associated ulcers. - Gastric and duodenal ulcer. - Zollinger-Ellison Syndrome and other pathological hyper secretory conditions. 4.2 Posology and method of administration Posology Adults and adolescents 12 years of age and above Reflux oesophagitis One tablet of Pantoprazole per day. In individual cases the dose may be doubled (increase to 2 tablets Pantoprazole daily) especially when there has been no response to other treatment. A 4-week period is usually required for the treatment of reflux oesophagitis. If this is not sufficient, healing will usually be achieved within a further 4 weeks. Adults Eradication of H. pylori in combination with two appropriate antibiotics In H. pylori positive patients with gastric and duodenal ulcers, eradication of the germ by a combination therapy should be achieved. Considerations should be given to official local guidance (e.g. national recommendations) regarding bacterial resistance and the appropriate use and prescription of antibacterial agents. Depending upon the resistance pattern, the following combinations can be recommended for the eradication of H. pylori: a) Twice daily one tablet Pantoprazole + twice daily 1000 mg amoxicillin + twice daily 500 mg c...